Adhesion of Monocytes to Arterial Endothelium and Initiation of Atherosclerosis Are Critically Dependent on Vascular Cell Adhesion Molecule-1 Gene Dosage
- 1 October 2001
- journal article
- other
- Published by Wolters Kluwer Health in Arteriosclerosis, Thrombosis, and Vascular Biology
- Vol. 21 (10) , 1662-1667
- https://doi.org/10.1161/hq1001.096625
Abstract
Vascular cell adhesion molecule-1 (VCAM-1/Vcam1) is a cytokine-inducible member of the immunoglobulin gene superfamily that is expressed by arterial endothelial cells in regions predisposed to athe...Keywords
This publication has 18 references indexed in Scilit:
- A major role for VCAM-1, but not ICAM-1, in early atherosclerosisJournal of Clinical Investigation, 2001
- Apo A-I inhibits foam cell formation in apo E–deficient mice after monocyte adherence to endotheliumJournal of Clinical Investigation, 1999
- The combined role of P- and E-selectins in atherosclerosis.Journal of Clinical Investigation, 1998
- Absence of P-selectin delays fatty streak formation in mice.Journal of Clinical Investigation, 1997
- Vascular cell adhesion molecule‐1 expression by hematopoiesis‐supporting stromal cells is not essential for lymphoid or myeloid differentiation in vivo or in vitroEuropean Journal of Immunology, 1996
- Decreased atherosclerosis in mice deficient in both macrophage colony-stimulating factor (op) and apolipoprotein E.Proceedings of the National Academy of Sciences, 1995
- Modified low density lipoprotein and its constituents augment cytokine-activated vascular cell adhesion molecule-1 gene expression in human vascular endothelial cells.Journal of Clinical Investigation, 1995
- Targeted disruption of the murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation.Genes & Development, 1995
- Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse.Proceedings of the National Academy of Sciences, 1994
- Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cellsPublished by Elsevier ,1992