Delayed Hemolytic Transfusion Reactions in Sickle Cell Anemia
- 1 August 1989
- journal article
- case report
- Published by Southern Medical Association in Southern Medical Journal
- Vol. 82 (8) , 1034-1036
- https://doi.org/10.1097/00007611-198908000-00025
Abstract
Delayed hemolytic transfusion reaction (DHTR) developed in three patients with sickle cell anemia seen over an 18-month period at Cook Country Hospital. The DHTR was associated with severe pain crisis, with spherocytic hemolytic anemia, a positive direct antiglobulin test result, previously undetected erythrocyte alloantibodies, and disappearance of Hb A on cellulose acetate electrophoresis. Delayed hemolytic transfusion reactions may be more common than is generally recognized and should be considered when a patient has a sickle cell pain crisis shortly after receiving a transfusion.Keywords
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