Antiretroviral Effects of Nonderivatizcd C6oIn Vitro
- 1 August 1997
- journal article
- research article
- Published by Taylor & Francis in Fullerene Science and Technology
- Vol. 5 (5) , 969-976
- https://doi.org/10.1080/15363839708013310
Abstract
We have observed thai nonderivatized C60 (buckminsterfullerene) could inhibit the replication of simian immunodeficiency virus (SIV) in vitro and the activity of Moloney murine leukemia virus (M-MuLV) reverse transcriptase (RT) (IC50 ≈3 μM). This means that biological effects are exerted via a direct and active interaction of the C6o skeleton with other macromolecules.Keywords
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