IMPROVEMENT OF DISABILITY AND AKINESIA OF PATIENTS WITH PARKINSONS-DISEASE BY INTRAVENOUS IRON SUBSTITUTION

  • 1 January 1987
    • journal article
    • research article
    • Vol. 17  (1) , 32-35
Abstract
Akinetic crises are one of the problems arising in patients with Parkinson''s disease in particular after long term treatment with levo-dihydroxyphenylalanine (L-DOPA). They are characterized by severe disability to move. Increasing dosages of L-DOPA and decarboxylase or monoaminooxidase inhibitors do not improve these symptoms. Intravenously applied iron in the form of a ferri-ferro-complex exhibits a considerable benefit for all patients treated so far. They regained a remarkable mobility. Their disability score dropped from up to 90 percent down to 30 percent. The effect is dosage-dependent, and withdrawal of iron will lead again to akinetic crises.

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