D‐Serine inhibits serine palmitoyltransferase, the enzyme catalyzing the initial step of sphingolipid biosynthesis
Open Access
- 23 May 2000
- journal article
- Published by Wiley in FEBS Letters
- Vol. 474 (1) , 63-65
- https://doi.org/10.1016/s0014-5793(00)01579-9
Abstract
Serine palmitoyltransferase (SPT), responsible for the initial step of sphingolipid biosynthesis, catalyzes condensation of palmitoyl coenzyme A and L‐serine to produce 3‐ketodihydrosphingosine (KDS)...Keywords
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