The effect of minocycline onCandida albicans
Open Access
- 1 April 1974
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 27 (4) , 269-272
- https://doi.org/10.1136/jcp.27.4.269
Abstract
Minocycline, a new tetracycline derivative, was found to inhibit the growth of Candida albicans. Inhibition was much affected by the composition of the medium and was difficult to demonstrate in fluid cultures. Study of the rate of budding in shallow broth cultures in Petri dishes showed that the addition of 20 μg/ml minocycline prolonged the lag phase by three hours. C. tropicalis was similarly inhibited and C. guilliermondii and C. parapsilosis to a lesser degree. Six other tetracyclines were tested and found to inhibit Candida only in very high concentrations.Keywords
This publication has 3 references indexed in Scilit:
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- Susceptibility of Common Pathogenic Bacteria to Seven Tetracycline Antibiotics in VitroThe Lancet Healthy Longevity, 1968
- The 6-Deoxytetracyclines. VII. Alkylated Aminotetracyclines Possessing Unique Antibacterial ActivityJournal of Medicinal Chemistry, 1967