Anti‐Lu14: A Lutheran Antibody Defining the Product of an Allele at the Lu8 Blood Group Locus1

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Abstract
A new Lutheran-related antibody, named anti-Lu14, reacts with approximately 2.4% of random bloods. Red cells of the rare Lu:-8 phenotype are Lu:14. The Lu 14 antigen is probably a product of an allele of Lu8 and Lu14 and Lu8 comprise a 3rd pair of alleles at the Lutheran locus. Red cells of the original Sw (a+) propositus are Lu:14. By coincidence, he inherited 2 low-incidence genes. This observation may explain the discrepancy in different families concerning a possible relationship between Swa and Lutheran. Pedigree information now suggests that Swa is not a Lutheran gene.