Sexual behaviour and high risk human papillomavirus infections in Japanese women

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Abstract
To investigate the prevalence of STIs, we performed a cross sectional study of women attending gynaecology departments in the Hokuriku area of Japan from July 2000 to July 2003. In all, 797 women between 15 and 62 years old were selected from about 15 000 women who had visited and had a cervical cytology test in one of five clinics during this period. After obtaining written informed consent, all the subjects were given to pelvic examinations, a cervical cytology test, and an STI test using the cervical scraped cell samples. DNA for high risk HPV (HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68), Chlamydiatrachomatis, and Neisseriagonorrhoeae was detected using hybrid capture assays (Digene, USA) performed at the Mitsubishi Kagaku Clinical Laboratory in Tokyo (Japan). To document each subject’s occupation and sexual behaviour, they were given a questionnaire that they completed independently and returned in a sealed envelope. The questionnaires and clinical data were sent directly to the research centre at Kanazawa University. All of the subjects had the right to refuse to answer any question. Out of 797 subjects, 16 were not eligible owing to lack of information or refusal to complete the questionnaire, and finally 781 women were evaluated in this study.

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