Prediction of Tablet Properties by Compression Force-Time Profile Parameters
- 1 January 1990
- journal article
- research article
- Published by Taylor & Francis in Drug Development and Industrial Pharmacy
- Vol. 16 (2) , 231-241
- https://doi.org/10.3109/03639049009114882
Abstract
The compression force-time profile parameters proposed by Chilamkurti el al. (1) have proved to be no better than maximum compression force for prediction of the properties of three series of direct compression microcrystalline cellulose tablet formulations containing various proportions of prednisone, phenobarbital or isoniazide and punched under various compression forces. The usefulness of the Chilamkurti parameters is nevertheless not ruled in the case of formulations for which maximum compression force has little predictive value.This publication has 3 references indexed in Scilit:
- Some Studies on Compression Properties of Tablet Matrices Using a Computerized Instrumented PressDrug Development and Industrial Pharmacy, 1982
- Computer Optimization of Pharmaceutical Formulations II: Application in TroubleshootingJournal of Pharmaceutical Sciences, 1973
- Computer Optimization of Pharmaceutical Formulations I: General procedureJournal of Pharmaceutical Sciences, 1973