Inhibition of enzymatic reduction of Δ14‐double bond of 5α‐cholesta‐8,14‐dien‐3β‐ol and 5α‐cholesta‐7,14‐dien‐3β‐ol by AY‐9944
- 1 January 1975
- Vol. 10 (1) , 9-11
- https://doi.org/10.1007/bf02532186
Abstract
AY-994 (trans-1,4-bis-[2-chlorobenzyl-aminomethyl] cyclohexane dihydrochloride), a potent inhibitor of the enzymatic reduction of the Δ7-double bond of Δ5,7-sterols, has been shown to inhibit, at higher concentrations (10−4 M), the enzymatic reduction of the Δ14-double bond of cholesta-8,14-dien-3β-ol and cholesta-7,14-dien-3β-ol.Keywords
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