Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8
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- 1 January 2002
- journal article
- Published by Wolters Kluwer Health
- Vol. 95 (1-2) , 143-152
- https://doi.org/10.1016/s0304-3959(01)00391-8
Abstract
Neuropathic pain is a debilitating chronic syndrome that often arises from injuries to peripheral nerves. Such pain has been hypothesized to be the result of an aberrant expression and function of sodium channels at the site of injury. Here, we show that intrathecal administration of specifiKeywords
This publication has 30 references indexed in Scilit:
- A Novel Persistent Tetrodotoxin-Resistant Sodium Current In SNS-Null And Wild-Type Small Primary Sensory NeuronsJournal of Neuroscience, 1999
- The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathwaysNature Neuroscience, 1999
- 5HT4Receptors Couple Positively to Tetrodotoxin-Insensitive Sodium Channels in a Subpopulation of Capsaicin-Sensitive Rat Sensory NeuronsJournal of Neuroscience, 1997
- PGE2 modulates the tetrodotoxin‐resistant sodium current in neonatal rat dorsal root ganglion neurones via the cyclic AMP‐protein kinase A cascade.The Journal of Physiology, 1996
- Co-expression of nociceptor properties in dorsal root ganglion neurons from the adult rat in vitroNeuroscience, 1996
- Hyperalgesic agents increase a tetrodotoxin-resistant Na+ current in nociceptors.Proceedings of the National Academy of Sciences, 1996
- A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neuronsNature, 1996
- Local anesthetics as adjuvant analgesicsJournal of Pain and Symptom Management, 1994
- Quantitative assessment of tactile allodynia in the rat pawJournal of Neuroscience Methods, 1994
- Characterization of TTX‐sensitive and TTX‐resistant sodium currents in small cells from adult rat dorsal root ganglia.The Journal of Physiology, 1993