Das primär doppelseitige maligne Melanom der Chorioidea - Fallbericht mit einem Beitrag zur Histogenèse des Tumors

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Abstract
An extremely rare case of primary bilateral malignant melanoma of the choroid with histological verification of both tumors is reported. The patient was a 54-yr-old woman; the presumptive clinical diagnosis was a primary bilateral melanoblastoma. A thorough general examination did not reveal any metastases. After 6 mo. the patient underwent surgery. The left eye, in which the tumor was larger, was enucleated and a B-type malignant melanoma of the choroid with invasion of the sclera was diagnosed histologically. After 2 mo., the patient died of a lung embolism. Histological verification of the tumor of the right eye led to the same diagnosis as in the left eye, but without invasion of neighboring structures. No distant metastases were found at autopsy. A thin layer of slender spindle nevus cells was found between the tumor and the sclera during the histological study. This may have been the origin of the malignant tumor.

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