An exfoliative cytologic study of intracranial fluids

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Abstract
A total of 76 samples of intracranial fluid were examined by conventional methods of exfoliative cytology; 46 were from patients with intracranial neoplasms. Tumor cells were recovered from 9. Cells of metastatic intracranial neoplasms of epithelial origin are more likely to be recovered than those of gliomas. Morphologic differences between the exfoliated cells of metastatic epithelial neoplasms and gliomas are brought out. The value of finding tumor cells in intracranial fluids is greatest in obscure diagnostic problems when localized intracranial tumors are not detectable; this situation is particularly liable to occur with metastatic brain tumors.