Determination of the Solution Conformation of Adenosine 2′:3′‐Monophosphate by Nuclear Magnetic Resonance with Lanthanide Probes
- 1 April 1977
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 74 (2) , 337-341
- https://doi.org/10.1111/j.1432-1033.1977.tb11398.x
Abstract
The aqueous solution conformation of adenosine 2′:3′‐monophosphate at pH 2.5 has been determined by a nuclear magnetic resonance method utilizing lanthanide ions as shift and relaxation probes. The ribose conformation is best described as a rapid equilibrium of 2′‐endo(3′‐exo) and 3′‐endo(2′‐exo) conformations in a ratio of approximately 2 to 1. The orientation of the base relative to to ribose is restricted to a narrow range about χcn=−70°.This publication has 19 references indexed in Scilit:
- Conformation of cyclic .beta.-adenosine 3',5'-phosphate in solution using the lanthanide shift techniqueJournal of the American Chemical Society, 1974
- Quantitative determination of the conformation of cyclic 3′,5′-adenosine monophosphate in solution using lanthanide ions as nuclear magnetic resonance probesJournal of Molecular Biology, 1974
- Molecular orbital calculations on the conformation of nucleic acids and their constituents: VIII. Conformations of 2′,3′- and 3′,5′-cyclic nucleotidesBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1973
- Carbon-13 and proton nuclear magnetic resonance study of the conformations of 2',3'-cyclic nucleotidesJournal of the American Chemical Society, 1973
- Structural chemistry of cyclic nucleotides. III. Proton magnetic resonance studies of .beta.-pyrimidine nucleotidesJournal of the American Chemical Society, 1973
- Structural chemistry of cyclic nucleotides. II. Crystal and molecular structure of sodium .beta.-cytidine 2',3'-cyclic phosphateJournal of the American Chemical Society, 1973
- Determination of the molecular conformation of uridine in aqueous solution by proton magnetic resonance spectroscopy. Comparison with β-pseudouridineCanadian Journal of Chemistry, 1970
- Cyclic Cytidine 2′,3′-Phosphate: Molecular StructureScience, 1970
- Stereochemistry of a substrate for pancreatic ribonuclease. Crystal and molecular structure of the triethylammonium salt of uridine 2', 3'-0,0-cyclophosphorothioateJournal of the American Chemical Society, 1970
- Crystal Structure of Uridine 2′,3′‐O,O‐CyclophosphorothioateAngewandte Chemie International Edition in English, 1969