Antiserum to Somatostatin Prevents Stress-Induced Inhibition of Growth Hormone Secretion in the Rat
- 7 May 1976
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 192 (4239) , 565-567
- https://doi.org/10.1126/science.1257793
Abstract
Plasma growth hormone levels fall and remain low for several hours after stress in the rat. When antiserums to somatostatin are administered to rats prior to stress, growth hormone secretory pulses are partially restored. The results provide evidence that circulating somatostatin plays a prominent role in stress-induced inhibition of growth hormone secretion in the rat.This publication has 20 references indexed in Scilit:
- Physiological role of somatostatin in the control of growth hormone and thyrotropin secretionBiochemical and Biophysical Research Communications, 1976
- Somatostatin: Abundance of Immunoreactive Hormone in Rat Stomach and PancreasScience, 1975
- Long-term Infusion of Growth Hormone Release Inhibiting Hormone in Acromegaly: Effects on Pituitary and Pancreatic HormonesBMJ, 1974
- Pulsatile Growth Hormone Secretion: Suppression by Hypothalamic Ventromedial Lesions and by Long-Acting SomatostatinScience, 1974
- Effect of Synthetic Somatotropin Release Inhibiting Factor on the Increase in Plasma Growth Hormone Elicited by L-Dopa in the DogEndocrinology, 1974
- Effects of Somatostatin on Plasma Glucose and Glucagon Levels in Human Diabetes MellitusNew England Journal of Medicine, 1974
- Effect of Somatostatin in Patients with AcromegalyNew England Journal of Medicine, 1974
- INHIBITION OF GROWTH HORMONE RELEASE IN HUMANS BY SOMATOSTATIN.Journal of Clinical Endocrinology & Metabolism, 1973
- Hypothalamic Polypeptide That Inhibits the Secretion of Immunoreactive Pituitary Growth HormoneScience, 1973
- Effect of Stress and Hypothalamic Deafferentation on the Secretion of Growth Hormone in the RatNeuroendocrinology, 1973