Ischaemic Paralysis of a Uniform Nerve

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Abstract
Summary.: The ischaemic blocking of a sensory nerve (the surd nerve) in the rabbit was investigated. The survival time was determined by recording sensory impulses elicited by stimulating skin receptors.In amputation and trachea clamp experiments the survival time as longer in short stretches of ischaemic nerve than in long stretches. This difference was shoirn to be due to oxygen leakage. In tourniquet experinients, where oxygen leakage was prevented, long and short stretches survived for equal times. Thus no gradient in sensitivity to ischaemia in the sural nerve v‐as found. The questions of temperature gradient in the leg, of pressure of the tourniquet upon the nerve and of end organ paralysis were all investigated and shown to be without effect upon ischaemic paralysis in the conditions of these experiments.In spite of the fact that no gradient in ischaemia‐sensitivity in the nerve was found, the proximal part of the surd area responded some 3–7 minutes longer than the distal.Fibres from slomly adapting receptors were blocked later than fibres from hair touch receptors, although the conduction rates of “hair touch fibres” were shown to overlap completely those of “slowly adapting fibres”.The findings in the present paper are compared with earlier investigations.

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