Crystallization and preliminary X-ray analysis of the thymidylate kinase fromMycobacterium tuberculosis
- 1 February 2000
- journal article
- research article
- Published by International Union of Crystallography (IUCr) in Acta Crystallographica Section D-Biological Crystallography
- Vol. 56 (2) , 226-228
- https://doi.org/10.1107/s0907444999016212
Abstract
Mycobacterium tuberculosis thymidylate kinase complexed with the substrate deoxythymidine monophosphate was crystallized in the hexagonal space group P6(5)22 or P6(1)22, with unit-cell parameters a = b = 76.62, c = 134.38 A and one single monomer of 23 kDa in the asymmetric unit. Cryo-cooled crystals diffract at 1.94 A resolution using synchrotron radiation.Keywords
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