Radiation therapy combined with adriamycin or 5-fluorouracil for the treatment of locally unresectable pancreatic carcinoma
- 1 December 1985
- Vol. 56 (11) , 2563-2568
- https://doi.org/10.1002/1097-0142(19851201)56:11<2563::aid-cncr2820561104>3.0.co;2-0
Abstract
One hundred fifty-seven patients with locally unresectable pancreatic carcinoma were randomly allocated to therapy with radiation and 5-fluorouracil or radiation and Adriamycin (doxorubicin). A total of 138 of 143 analyzable patients have died, and no differences in the relative survival impact of the treatments have been observed (P > 0.8). Toxicity on the Adriamycin arm was more substantial (P < 0.05) and primarily attributable to Adriamycin chemotherapy after the completion of radiotherapy.Keywords
This publication has 10 references indexed in Scilit:
- THE MANAGEMENT OF PANCREATIC CARCINOMA: A REVIEW OF 173 CASESAnz Journal of Surgery, 1983
- Fast neutron irradiation for locally advanced pancreatic cancerInternational Journal of Radiation Oncology*Biology*Physics, 1981
- Therapy of locally unresectable pancreatic carcinoma: A randomized comparison of high dose (6000 rads) radiation alone, moderate dose radiation (4000 rads + 5-fluorouracil), and high dose radiation + 5-fluorouracil. The gastrointestinal tumor study groupCancer, 1981
- New surgical approaches to pancreatic cancerCancer, 1981
- Modified Kolmogorov-Smirnov Test Procedures with Application to Arbitrarily Right-Censored DataPublished by JSTOR ,1980
- Randomized phase II clinical trial of adriamycin, methotrexate, and actinomycin-d in advanced measurable pancreatic carcinoma.A gastrointestinal tumor study group reportCancer, 1978
- Radiation therapy in the treatment of irresectable adenocarcinoma of the pancreasCancer, 1973
- Regression Models and Life-TablesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1972
- COMBINED 5-FLUOROURACIL AND SUPERVOLTAGE RADIATION THERAPY OF LOCALLY UNRESECTABLE GASTROINTESTINAL CANCERThe Lancet, 1969
- A generalized Wilcoxon test for comparing arbitrarily singly-censored samplesBiometrika, 1965