Neonatal Hydrocortisone Administration: Effect on Cortisol and Glucose Levels

Abstract
Mean plasma cortisol levels were 314 and 553 μg/100ml 1 h after intramuscular hydrocortisone hemisuccinate 12.5 and 25 mg respectively, and significant levels were still present 10 h later. Half-life values in the period 2–8 h after injection range from 116 to 218 min with a mean of 147 min. Mean blood glucose increased by 12 mg/100 ml 2 h after injection.

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