Studies on the Chemistry of Human Platelet Factor 4
- 1 January 1977
- journal article
- research article
- Published by S. Karger AG in Pathophysiology of Haemostasis and Thrombosis
- Vol. 6 (1) , 53-58
- https://doi.org/10.1159/000214165
Abstract
The chemical characteristics of several PF4 preparations have been examined by gel electrophoresis, amino acid analysis and NH2-terminal amino acid sequence determination. Preparations of PF4 from gel filtration and from affinity chromatography appeared identical. A single NH2-terminal sequence was determined as follows: NH2-Glu-Ala-Glu-Glu-Asp-Gly-Asp-Leu-Gln-SCMCys-Leu-SCMCys-Val-Lys-Thr-Thr-Ser-Gln-Val-Arg-. The molecular weight of the PF4 subunits, which seem to be identical, was 7,100 based on the recovery of NH2-terminal glutamic acid.This publication has 2 references indexed in Scilit:
- The release of a human platelet specific protein measured by a radioimmunoassayThrombosis Research, 1975
- A Protein SequenatorEuropean Journal of Biochemistry, 1967