Embryotoxicity and Teratogenicity of Styrene and Styrene Oxide on Chick Embryos Enhanced by Trichloropropylene Oxide

1 November 1979

journal article
research article
Published by Wiley in Acta Pharmacologica et Toxicologica

Vol. 45 (5) , 399-402
https://doi.org/10.1111/j.1600-0773.1979.tb02408.x

Abstract

The effects of TCPO (trichloropropylene oxide) on the embryotoxicity and teratogenicity of styrene and styrene oxide on chick embryos were investigated. The compounds were injected into the air space of the eggs in a total volume of 25 μI on the third day of embryogenesis. TCPO increased embryotoxicity and teratogenicity of styrene and styrene oxide. Our results present evidence that the epoxides possess embryotoxic and teratogenic properties in chick embryos.

Keywords

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