Rotenoid synthesis, by one-carbon insertion, from 2′-hydroxyisoflavones using dimethylsulphoxonium methylide

Abstract
The vinylcoumaranone (V) formed when isoderritol isoflavone (I) reacts with dimethylsulphoxonium methylide (1 mol) is isomerised by pyridine to isorotenone (X): the new rotenoid synthesis has similarities to the biosynthetic route.

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