ABSENCE OF DIFFERENTIAL RNA SYNTHESIS BY THE X CHROMOSOMES OF COW LEUCOCYTES
- 1 March 1970
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Genetics and Cytology
- Vol. 12 (1) , 44-51
- https://doi.org/10.1139/g70-008
Abstract
The patterns of ribonucleic acid synthesis by the two X chromosomes during mitotic interphase were studied at metaphase. Cultured cow leucocytes were pulsed with H3-uridine for 15 minutes, washed, resuspended in tracer-free medium and collected at different times after the end of the pulse. Autoradiography of the cells failed to show any significant differences in the number of grains located over the two X chromosomes. The incorporation of H3-uridine into RNA by both X chromosomes indicates that at least part of the 'inactive' X chromosome must be actively synthesizing some RNA.Keywords
This publication has 4 references indexed in Scilit:
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- Synthesis of Ribonucleic Acid by Human Chromosomes and a Possible Mechanism of its RepressionNature, 1966
- URIDINE-5-H3 RADIOAUTOGRAPHY OF THE HUMAN SEX CHROMATIN BODYThe Journal of cell biology, 1966
- Mammalian X-Chromosome Action: Inactivation Limited in Spread and in Region of OriginScience, 1963