Change in PaO2 During Artificial Ventilation With Added Dead Space
- 11 December 1969
- journal article
- Published by Wiley in Acta Anaesthesiologica Scandinavica
- Vol. 13 (4) , 241-246
- https://doi.org/10.1111/j.1399-6576.1969.tb00446.x
Abstract
SUMMARY: When patients during anaesthesia were ventilated with large tidal volumes which produced a mean PaCO2 of 26 mm Hg, insertion of a 500 ml dead space increased PaCO2 to 48 mm Hg, and was accompanied by a rise in PaO2 from 172 mm Hg to 212 mm Hg, probably caused by an increase in cardiac output.It is suggested that a state of normocapnia should be attempted when respiration and circulation are interfered with, as under anaesthesia.ZUSAMMENFASSUNG: Wenn Patienten in Narkose mit so grossen Atemvolumina beatmet werden, dass ein durchschnittliches PaCO2 von 26 mm Hg resultiert, kann man durch Zwischenschalten eines Totraumes von 500 ml das PaCO2 wieder auf 48 mm Hg erhöhen. Dies ist von einem PaO2‐Anstieg von 172 mm Hg auf 212 mm Hg begleitet, der wahrscheinlich die Folge eines erhohten Herzminutenvolumens ist.Es wird vorgeschlagen, einen Zustand der Normokapnie anzustreben, wenn, wie unter der Narkose, die Atem‐ und Kreislaufverhältnisse gestört sind.Keywords
This publication has 17 references indexed in Scilit:
- Influence of duration of hyperventilation on rise time of PCO2, after step reduction of ventilationRespiration Physiology, 1968
- Change in PaCO2 with mechanical dead space during artificial ventilation.Journal of Applied Physiology, 1968
- Splanchnic Circulation During Nitrous Oxide Anesthesia and Hypocarbia in Normal ManAnesthesiology, 1968
- The influence of circulatory factors on arterial oxygenation during anaesthesia in man*Anaesthesia, 1967
- New Formulas for Ventilation of the Anesthetized PatientAnesthesiology, 1966
- FACTORS INFLUENCING THE ARTERIAL OXYGEN TENSION DURING HALOTHANE ANAESTHESIA WITH SPONTANEOUS RESPIRATIONBritish Journal of Anaesthesia, 1964
- Impaired Oxygenation in Surgical Patients during General Anesthesia with Controlled VentilationNew England Journal of Medicine, 1963
- RELATIONSHIPS OF PYRUVATE AND LACTATE DURING ANAEROBIC METABOLISM. I. EFFECTS OF INFUSION OF PYRUVATE OR GLUCOSE AND OF HYPERVENTILATION1Journal of Clinical Investigation, 1958
- Clinical Use of a Nomogram to Estimate Proper Ventilation during Artificial RespirationNew England Journal of Medicine, 1954
- THE EFFECTS OF ALTERED ARTERIAL TENSIONS OF CARBON DIOXIDE AND OXYGEN ON CEREBRAL BLOOD FLOW AND CEREBRAL OXYGEN CONSUMPTION OF NORMAL YOUNG MEN 1Journal of Clinical Investigation, 1948