Chromosome banding and compaction
- 1 April 1981
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 57 (2) , 199-202
- https://doi.org/10.1007/bf00282022
Abstract
We have described a characteristic substructure of mitotic chromosomes, the chromosomal unit fibre, with lengths about five times the length of the corresponding metaphase chromosomes and a uniform diameter of 0.4 μm. In order to study the relationship of chromosome banding to chromosome compaction, methods have been devised to obtain banding patterns on chromosomal unit fibres, similar to G-band patterns of intact mitotic chromosomes. The total number of bands plus interbands per haploid human karyotype is estimated at about 3000. The banding pattern of chromosomal unit fibres indicates a certain resemblance to the normal G-banding pattern of human chromosomes even if the details indicate a short-range random distribution.Keywords
This publication has 14 references indexed in Scilit:
- Chromosomal unit fibers in DrosophilaChromosoma, 1979
- Characterization of human chromosomal unit fibersChromosoma, 1979
- G-banding patterns of high-resolution human chromosomes 6?22, X, and YHuman Genetics, 1979
- Higher levels of organization in chromosomesJournal of Theoretical Biology, 1979
- MECHANISMS OF CHROMOSOME BANDING AND IMPLICATIONS FOR CHROMOSOME STRUCTUREAnnual Review of Genetics, 1978
- The characterization of high-resolution G-banded chromosomes of manChromosoma, 1978
- Structure of ChromatinAnnual Review of Biochemistry, 1977
- Higher-order structure of human mitotic chromosomes.Proceedings of the National Academy of Sciences, 1977
- High Resolution of Human ChromosomesScience, 1976
- Staining of Satellite DNA in Metaphase ChromosomesNature, 1971