Radiation damage in protein crystals at low temperature

1 November 1994

journal article
research article
Published by International Union of Crystallography (IUCr) in Acta Crystallographica Section D-Biological Crystallography

Vol. 50 (6) , 874-877
https://doi.org/10.1107/s0907444994006311

Abstract

This paper describes the study of the effects of radiation damage on the quality of data collected from a protein crystal at 100 K. It is shown that radiation damage causes measurable effects in the diffraction pattern. This implies that, even at liquid nitrogen temperatures, there is a limit to the size of a crystal from which a complete data set can be collected.

Keywords

RADIATION DAMAGE
LIQUID NITROGEN
PROTEIN CRYSTAL
EFFECTS OF RADIATION
MEASURABLE EFFECTS
LOW TEMPERATURE