EFFECT OF HEPARIN ON INSULIN SECRETION INDUCED BY GLUCOSE IN DOGS
- 1 March 1974
- journal article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 75 (3) , 531-538
- https://doi.org/10.1530/acta.0.0750531
Abstract
In anaesthetized dogs, heparin given intravenously in a dose of 100 IU/kg 10 min before an ivGTT (0.5 g/kg) inhibited glucose-stimulated insulin secretion as measured in portal and peripheral venous blood. Thus glucose assimilation is reduced. However there was a considerable antilipolytic action of the small quantity of secreted insulin as shown by the diminution of FFA concentration.Keywords
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