SERUM CONCENTRATIONS OF VITAMIN B_12 IN ACUTE LEUKEMIA

Abstract
Serum concentrations of vit. B12 in acute leukemia were studied using Euglena gracilis as test organism. The mean concentration in 11 cases of acute lymphatic leukemia was 270 [mu][mu]g./ml. the mean concentration in acute myelocytic leukemia was 2760 [mu][mu]g./ml., or approximately 13 times the mean for normal sera. Acute monocytic leukemia had a mean serum vit. B12 concentration of 650 [mu][mu]g./ml. This blood level is not related to the total leukocyte count. The significance of these findings is discussed.

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