CYTOLOGIC DETECTION OF BLADDER-CANCER IN A RURAL EGYPTIAN POPULATION INFESTED WITH SCHISTOSOMIASIS

  • 1 January 1982
    • journal article
    • research article
    • Vol. 26  (3) , 303-310
Abstract
A study was initiated to detect early bladder carcinoma by selective cytologic screening in a rural Egyptian population infested with Schistosoma haematobium. All persons in a high-risk group, i.e., farmers aged 20 yr and above, and selected persons from 2 low-risk groups, were screened. Bladder carcinoma was detected in 11 patients among the 4769 individuals screened in the high-risk group for a yield of 2.3/1000. No tumors were detected in the 3975 individuals in the low-risk groups. Cytologically diagnosed tumors were verified by histology in all cases. One of the detected tumors in a female was metastatic from carcinoma of the cervix. The primary tumors included 5 squamous cell carcinomas, 4 transitional cell carcinomas and 1 undifferentiated carcinoma. Seven of the tumors were at early stages, including 3 noninvasive (TIS) and 4 superficial (T1 and T2) ones. Selective cytologic screening in the high-risk group in Egypt is feasible and effective for the early detection of bladder carcinoma associated with schistosomiasis.

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