THE EFFECT OF PROPRANOLOL ON THYROID HORMONES AND OXYGEN CONSUMPTION IN THYROTOXICOSIS

Abstract
The possibly that propranolol may exert its beneficial actions in thyrotoxicosis by an effect on thyroid hormone concentrations was investigated by measuring these and O consumption in a group of thyrotoxic patients before and after propranolol treatment. Following treatment a significant fall in plasma T3 [triiodothyronine] concentration and O consumption occurred and a direct correlation was found between these 2 variables. Propranolol may, therefore, exert some of its beneficial effects in thyrotoxicosis by an action on T3 metabolism.