Failure of Infused Prolactin To Prolong the Life Span of the Corpus Luteum of the Ewe
- 1 July 1971
- journal article
- other
- Published by The Endocrine Society in Endocrinology
- Vol. 89 (1) , 272-275
- https://doi.org/10.1210/endo-89-1-272
Abstract
Experiments were conducted to compare the ability of continuous intravenous infusion of prolactin and luteinizing hormone (LH) to prolong maintenance of the corpus luteum of the cyclic ewe beyond its normal 16-day life span. Infusion of prolactin (2.5 or 5.0 nag/ day), LH (2.5 mg/day), or saline vehicle was started on day 12 after heat and continued until day 20. On day 20, all corpora lutea of salineinfused and prolactin-infused ewes were regressed. Two of the 4 ewes receiving LH had maintained corpora lutea which compared favorably in weight and progesterone content and concentration to corpora lutea of day 12 controls. The results show that exogenous LH may maintain corpora lutea of ewes in the presence of the uterus, whereas prolactin cannot do so. (Endocrinology89: 272, 1971)Keywords
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