A new carbamazepine metabolite in uraemic filtrate
- 1 January 1992
- journal article
- Published by Taylor & Francis in Xenobiotica
- Vol. 22 (8) , 1029-1035
- https://doi.org/10.3109/00498259209049908
Abstract
1. After administration of carbamazepine (Tegretal) to an epileptic patient suffering also from uraemia, a previously unknown metabolite was detected in the haemofiltrate. It was identified as the 10,11-dihydro-10-hydroxy-carbamazepine-O-beta-glucuronide. 2. Its identification was accomplished mainly by electron impact (EI), liquid secondary ion (LSI) mass spectrometry and n.m.r. spectroscopy.Keywords
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