Biosynthesis of terpenes and steroids. Part IV. Specific hydride shifts in the biosynthesis of lanosterol and β-amyrin
- 1 January 1971
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society C: Organic
- p. 1142-1148
- https://doi.org/10.1039/j39710001142
Abstract
The hydride shifts accompanying 2,3-epoxysqualene cyclisation to lanosterol in yeast and to β-amyrin in peas have been checked using 2,3-epoxy[11,14-3H2]squalene. The results support the Ruzicka–Eschenmoser hypothesis and not a plausible alternative which was considered. The synthesis of 2,3-epoxy[11,14-3H2]squalene by two routes is described.Keywords
This publication has 0 references indexed in Scilit: