Compact instrument for fluorescence image-guided surgery
Open Access
- 1 January 2010
- journal article
- research article
- Published by SPIE-Intl Soc Optical Eng in Journal of Biomedical Optics
- Vol. 15 (2) , 020509-020509-3
- https://doi.org/10.1117/1.3378128
Abstract
Fluorescence image-guided surgery (FIGS) is an emerging technique in oncology, neurology, and cardiology. To adapt intraoperative imaging for various surgical applications, increasingly flexible and compact FIGS instruments are necessary. We present a compact, portable FIGS system and demonstrate its use in cardiovascular mapping in a preclinical model of myocardial ischemia. Our system uses fiber optic delivery of laser diode excitation, custom optics with high collection efficiency, and compact consumer-grade cameras as a low-cost and compact alternative to open surgical FIGS systems. Dramatic size and weight reduction increases flexibility and access, and allows for handheld use or unobtrusive positioning over the surgical field.Keywords
This publication has 14 references indexed in Scilit:
- The FLARE™ Intraoperative Near-Infrared Fluorescence Imaging System: A First-in-Human Clinical Trial in Breast Cancer Sentinel Lymph Node MappingAnnals of Surgical Oncology, 2009
- Real‐time identification of liver cancers by using indocyanine green fluorescent imagingCancer, 2009
- High-Power, Computer-Controlled, Light-Emitting Diode–Based Light Sources for Fluorescence Imaging and Image-Guided SurgeryMolecular Imaging, 2009
- Imaging of Lymph Flow in Breast Cancer Patients after Microdose Administration of a Near-Infrared Fluorophore: Feasibility StudyRadiology, 2008
- Intraoperative Imaging Techniques to Assess Coronary Artery Bypass Graft PatencyThe Annals of Thoracic Surgery, 2007
- Fluorescent cholangiography in a mouse model: an innovative method for improved laparoscopic identification of the biliary anatomySurgical Endoscopy, 2006
- Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trialThe Lancet Oncology, 2006
- In vivo near-infrared fluorescence imagingPublished by Elsevier ,2003
- A multispectral fluorescence imaging system: Design and initial clinical tests in intra‐operative Photofrin‐photodynamic therapy of brain tumorsLasers in Surgery and Medicine, 2003
- QUANTITATIVE OPTICAL SPECTROSCOPY FOR TISSUE DIAGNOSISAnnual Review of Physical Chemistry, 1996