A Study of Sweat Sodium and Chloride; Criteria for the Diagnosis of Cystic Fibrosis
- 1 March 1985
- journal article
- research article
- Published by SAGE Publications in Annals of Clinical Biochemistry: International Journal of Laboratory Medicine
- Vol. 22 (2) , 171-174
- https://doi.org/10.1177/000456328502200212
Abstract
Retrospective analysis of sodium and chloride results from sweat tests carried out in Bristol and Sheffield has shown that misdiagnosis of cystic fibrosis (false negatives and false positives) is considerably less if sodium and chloride are both measured. In patients with cystic fibrosis the chloride concentration is usually higher than the sodium, whereas in normal subjects the reverse usually occurs. This observation is particularly useful when borderline results (50–70 mmol/L) are obtained.This publication has 7 references indexed in Scilit:
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- DOES THAT CHILD REALLY HAVE CYSTIC FIBROSIS?The Lancet, 1978
- A TEST FOR CONCENTRATION OF ELECTROLYTES IN SWEAT IN CYSTIC FIBROSIS OF THE PANCREAS UTILIZING PILOCARPINE BY IONTOPHORESISPediatrics, 1959