Ectopic Human Placental Lactogen and β-Human Chorionic Gonadotropin in Gastric Fluid of Patients with Malignant and Non-Malignant Conditions of the Stomach

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Abstract
Human placental lactogen (hPL) and β-human chorionic gonadotropin (β-hCG) in gastric aspirates and sera of 24 patients with malignant (12 patients) and non-malignant (12 patients) conditions of the stomach were studied. In patients with cancer of the stomach, hPL and β-hCGwere found to be present in gastric aspirate at higher frequency than in serum. The concentration of these hormones in gastric aspirate was higher than in serum. In 2 patients with duodenal ulcer β-hCGwas found to be present in gastric aspirate, 1 of them having the hormone in circulation as well, while none of the 12 patients with non-malignant conditions of the stomach showed presence of hPL in their gastric aspirate or serum.