THYMOXAMINE HYDROCHLORIDE - EFFECTS ON FACILITY OF OUTFLOW AND INTRAOCULAR-PRESSURE

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  • 1 January 1976
    • journal article
    • research article
    • Vol. 15  (5) , 400-403
Abstract
Subjects [11] with normal eyes and 16 with open-angle glaucoma had a selective .alpha.-adrenergic blocking agent, thymoxamine hydrochloride 0.5% eyedrop, applied to 1 of their eyes. This consistently produced miosis, but did not significantly alter the intraocular pressure or the tonographically determined facility of aqueous outflow. Thymoxamine can selectively induce miosis without significant accompanying effect on the ciliary muscle or facility of outflow, this drug may prove to be a useful diagnostic adjunct to gonioscopy in distinguishing between angle-closure glaucoma and open-angle glaucoma with narrow angle.

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