Imparting Bone Affinity to Glycoproteins Through the Conjugation of Bisphosphonates
- 1 January 2003
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 20 (7) , 978-987
- https://doi.org/10.1023/a:1024445903306
Abstract
Purpose. To develop a novel means of conjugating bisphosphonates onto the carbohydrate moieties of glycoproteins to enhance protein affinity to bone. Methods. 1-Amino-1,1-diphosphonate methane...Keywords
This publication has 36 references indexed in Scilit:
- Surface engineering of living myoblasts via selective periodate oxidationBiotechnology & Bioengineering, 2003
- Targeting Systemically Administered Proteins to Bone by Bisphosphonate ConjugationBiotechnology Progress, 2002
- Bone induction by Escherichia coli -derived recombinant human bone morphogenetic protein-2 compared with Chinese hamster ovary cell-derived recombinant human bone morphogenetic protein-2British Journal of Oral and Maxillofacial Surgery, 2000
- Clearance properties of liposomes involving conjugated proteins for targetingAdvanced Drug Delivery Reviews, 1998
- Development of a Streptavidin−Anti-Carcinoembryonic Antigen Antibody, Radiolabeled Biotin Pretargeting Method for Radioimmunotherapy of Colorectal Cancer. Reagent DevelopmentBioconjugate Chemistry, 1997
- The structural role of sugars in glycoproteinsCurrent Opinion in Biotechnology, 1996
- Effects of basic fibroblast growth factor (bFGF) on bone formation in growing ratsBone, 1995
- Calcium‐binding properties of fetuin in fetal bovine serumJournal of Experimental Zoology, 1994
- The Histopathology of Kidney Changes in Rats and Monkeys Following Intravenous Administration of Massive Doses of FCE 26184, Human Basic Fibroblast Growth FactorToxicologic Pathology, 1993
- A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye BindingAnalytical Biochemistry, 1976