Evidence That C1t (Amyloid P-Component) Is Not a Subcomponent of the First Component of Complement (C1)
Open Access
- 1 December 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 119 (6) , 2203-2205
- https://doi.org/10.4049/jimmunol.119.6.2203
Abstract
Summary: The recent observation that plasma P-component/C1t binds to agarose in a calcium-dependent fashion provided an opportunity to demonstrate that specific and selective removal of this protein from serum had no effect on the hemolytic or molecular properties of serum C1 activity. Thus, it is concluded that this protein does not form part of the C1 macromolecular complex.This publication has 3 references indexed in Scilit:
- ISOLATION OF AMYLOID P COMPONENT (PROTEIN AP) FROM NORMAL SERUM AS A CALCIUM-DEPENDENT BINDING PROTEINThe Lancet, 1977
- The unactivated form of the first component of human complement, C1Biochemical Journal, 1976
- The Ultrastructure of C1t, a Subcomponent of the First Component of Complement: An E.M. and Ultracentrifuge StudyThe Journal of Immunology, 1976