A two-way scanning method for total body in vivo neutron activation analysis

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Abstract
When determining the total body content of many elements by neutron activation analysis, irradiation and whole body counting by scanning along the length of the body has significant advantages. A neutron source of lower output and a whole body counter using smaller detectors and shielding (than otherwise needed) can provide a high, uniform response for many elements throughout the body. This was previously achieved by making the speed and direction of scanning identical in irradiation and counting (1-way scanning). A simple theoretical model for scanned irradiation and counting is described. The model is used to show that a scanning regime in which both scanning directions are used (2-way scanning) can provide acceptably uniform response for elements having induced activities of a wide range of half-life. This is supported by measurements made using an existing scanning facility for total body in vivo neutron activation analysis. The 2-way scanning regime offers the advantages of increased patient comfort, simpler operation and more efficient use of the time available for counting induced activity.