Lethal toxin fromClostridium sordelliiinduces apoptotic cell death by disruption of mitochondrial homeostasis in HL-60 cells
Open Access
- 1 November 2003
- journal article
- research article
- Published by Hindawi Limited in Cellular Microbiology
- Vol. 5 (11) , 761-771
- https://doi.org/10.1046/j.1462-5822.2003.00309.x
Abstract
Lethal toxin (LT) from Clostridium sordellii (strain IP82) inactivates in glucosylating the small GTPases Ras, Rap, Ral and Rac. In the present study we show that LT-IP82 induces cell death via an in...Keywords
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