Metabolic engineering of sugar catabolism in lactic acid bacteria
- 1 October 1996
- journal article
- Published by Springer Nature in Antonie van Leeuwenhoek
- Vol. 70 (2) , 223-242
- https://doi.org/10.1007/bf00395934
Abstract
Lactic acid bacteria are characterized by a relatively simple sugar fermentation pathway that, by definition, results in the formation of lactic acid. The extensive knowledge of traditional pathways and the accumulating genetic information on these and novel ones, allows for the rerouting of metabolic processes in lactic acid bacteria by physiological approaches, genetic methods, or a combination of these two. This review will discuss past and present examples and future possibilities of metabolic engineering of lactic acid bacteria for the production of important compounds, including lactic and other acids, flavor compounds, and exopolysaccharides.Keywords
This publication has 80 references indexed in Scilit:
- Characterization of pepR1, a gene coding for a potential transcriptional regulator of Lactobacillus delbrueckii subsp. lactis DSM7290FEMS Microbiology Letters, 1996
- Metabolic engineering of the Lactococcus lactis diacetyl pathwayLe Lait, 1996
- Autoregulation of Nisin Biosynthesis in Lactococcus lactis by Signal TransductionJournal of Biological Chemistry, 1995
- Dependence of Lactose Metabolism upon Mutarotase Encoded in the gal Operon in Escherichia coliJournal of Molecular Biology, 1994
- Lysines 72, 80 and 213 and aspartic acid 210 of the Lactococcus lactis LacR repressor are involved in the response to the inducer tagatose-6-phosphate leading to induction of lac operon expressionProtein Engineering, Design and Selection, 1993
- Molecular cloning and analysis of the gene encoding the NADH oxidase from Streptococcus faecalis 10C1: Comparison with NADH peroxidase and the flavoprotein disulfide reductasesJournal of Molecular Biology, 1992
- Cloning and overexpression of the Lactobacillus bulgaricus NAD+-dependent D-lactate dehydrogenase gene in Escherichia coli: Purification and characterization of the recombinant enzymeBiochemical and Biophysical Research Communications, 1992
- Cloning, sequence and overexpression of NADH peroxidase from Streptococcus faecalis 10C1: Structural relationship with the flavoprotein disulfide reductasesJournal of Molecular Biology, 1991
- Analysis of the lacZ sequences from two Streptococcus thermophilus strains: comparison with the Escherichia coli and Lactobacillus bulgaricus β-galactosidase sequencesMicrobiology, 1991
- Iron‐ and manganese‐containing superoxide dismutases can be distinguished by analysis of their primary structuresFEBS Letters, 1988