Kinetic studies on the interaction of streptokinase and other plasminogen activators with plasminogen and fibrin
- 15 July 1985
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 229 (2) , 555-558
- https://doi.org/10.1042/bj2290555
Abstract
The activation of Lys-plasminogen to plasmin by streptokinase was promoted by soluble fibrin such that Km was decreased and Vmax increased. Enhancement was also observed when Glu-plasminogen was the substrate and was shared by the preformed streptokinase-plasminogen activator complex, indicating that the stimulation was not exerted primarily on the rate of active site formation.This publication has 24 references indexed in Scilit:
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