Physicochemical Properties of Human Middle Ear Effusions (Mucus) and Their Relation to Ciliary Transport
- 1 May 1978
- journal article
- research article
- Published by Wiley in The Laryngoscope
- Vol. 88 (5) , 729-738
- https://doi.org/10.1002/lary.1978.88.5.729
Abstract
Middle ear effusions were collected from 10 patients (14 ears) with secretory otitis media. Mucoid samples were pooled and reconstituted to various concentrations of nondialyzable solids. Viscoelasticity was studied using a magnetic microrheometer and compared with mucociliary transport rates measured on the frog palate. Results indicate that the viscoelastic properties of middle ear mucus correlate with mucociliary transport. A transport maximum was found at a 2% nondialyzable solids content. Implications relative to ineffective mucociliary transport in secretory otitis media are discussed.Keywords
Funding Information
- Department of Otorhinolaryngology and Human Communication (5701-NS-057969)
- Department of Chemical and Biochemical Engineering (NHLI 14271-05)
This publication has 25 references indexed in Scilit:
- Middle ear pressures in eustachian tube malfunction: Manometric studiesThe Laryngoscope, 1973
- The experimental production of allergic middle ear effusionsThe Laryngoscope, 1973
- Biochemical Characterization of Middle Ear EffusionsAnnals of Otology, Rhinology & Laryngology, 1972
- Nature of the Fluid in Serous Otitis MediaJAMA Otolaryngology–Head & Neck Surgery, 1971
- Mucus RheologyArchives of internal medicine (1960), 1970
- Pathology and Pathogenesis of Serous Otitis MediaJAMA Otolaryngology–Head & Neck Surgery, 1966
- Middle Ear MucosaJAMA Otolaryngology–Head & Neck Surgery, 1966
- The Comparative Pathology of Otitis Media—Experimental and HumanThe Journal of Laryngology & Otology, 1955