Efficient electrophilic fluorination of β-dicarbonyl compounds with the selectfluor reagent F-TEDA-BF4{1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate)}
- 1 January 1994
- journal article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 3,p. 343-344
- https://doi.org/10.1039/c39940000343
Abstract
1,3-Dicarbonyl compounds (acyclic and cyclic 1,3-diketones, β-ketoesters, β-ketoamides) are converted efficiently to 2-monofluoro derivatives, and thence to 2,2-difluoro derivatives, with 1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate).Keywords
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