Syntheses and Insecticidal Activity of 8-Isopropyl-6-oxabicyclo[3.2.1]octan-7-one, a Partial Skeleton of Picrotoxinin, and Related Compounds
- 1 February 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in Agricultural and Biological Chemistry
- Vol. 44 (2) , 383-386
- https://doi.org/10.1080/00021369.1980.10863937
Abstract
The title lactone trans-7 with a partial structural resembling picrotoxinin 1, which is an antagonist of GABA, and some related lactones were synthesized, and their insecticidal activities were assayed on susceptible and resistant housefly strains. Lactone trans-7 showed the highest activity among the tested compounds in both strains. The configuration of the isopropyl group at C8 position was important for the insecticidal activity.This publication has 1 reference indexed in Scilit:
- Structure and insecticidal activity of picrotoxinin analogsPesticide Biochemistry and Physiology, 1979