A Nasal Critical-Size Defect

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Abstract
DEFECTS IN the facial structural framework are common and challenging problems for otolaryngologist–head and neck surgeons that occur as a result of congenital malformation, trauma, infection, and the surgical resection of neoplastic disease. Current materials for repairing these defects involve autogenous bone and cartilage, allograft bone, and synthetic alloplasts. At present, however, all of these techniques have potentially serious drawbacks ranging from unpredictable resorption and migration of the implant to a second surgical site to the possibility of viral transference. The ideal method of repair has yet to be developed.

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