Intense Concentration of Technetium-99m Pyrophosphate in the Kidneys of Children Treated with Chemotherapeutic Drugs for Malignant Disease
- 1 July 1978
- journal article
- research article
- Published by Radiological Society of North America (RSNA) in Radiology
- Vol. 128 (1) , 165-167
- https://doi.org/10.1148/128.1.165
Abstract
Seventeen of 265 bone scans in children receiving chemotherapy for various malignant diseases exhibited intense renal parenchymal uptake of radioactivity during bone imaging. In a retrospective analysis, it was learned that uptake occurred when imaging was performed within 1 wk of cancer chemotherapy. It was encountered after injection of cyclophosphamide (P < 0.05), vincristine (P < 0.01) and doxorubicin (P < 0.02). None of the 265 scans showed intense renal uptake unless the patient received chemotherapeutic drugs in the preceding week. This finding did not seem to result from altered renal function, and the exact cause was not defined.This publication has 3 references indexed in Scilit:
- Doxorubicin hydrochloride-associated renal failureArchives of internal medicine (1960), 1977
- Adriamycin cardiotoxicity in children.Case reports, literature review, and risk factorsCancer, 1977
- Water Intoxication in Man After Cyclophosphamide TherapyAnnals of Internal Medicine, 1973