ACACIA IN THE TREATMENT OF NEPHROSIS

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Abstract
The use of acacia intravenously in the treatment of edema due to nephrosis has been advocated.1The rationale of this treatment is based on the fact that acacia is an inert colloid which, when introduced into the blood stream, will raise the osmotic pressure of the blood above the levels at which edema occurs. The theory is logical, but our experiences with its use have been disappointing. Acacia in amounts approximating 1 Gin. per kilogram of ideal body weight has been given intravenously to four children with nephrosis in order to combat edema. The first administration of acacia was markedly effective, but not only were succeeding injections progressively less effective in reducing edema but other unfavorable symptoms developed. In each child the liver became markedly enlarged and tender, and simultaneously with a period of acacia treatment the serum protein, particularly the albumin fraction, dropped to dangerously low limits, remaining

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