LASTING BIOLOGICAL EFFECTS OF EARLY ENVIRONMENTAL INFLUENCES
Open Access
- 1 February 1972
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 135 (2) , 220-234
- https://doi.org/10.1084/jem.135.2.220
Abstract
The metabolism of adenosine 3',5'-monophosphate (cyclic AMP) was studied in specific pathogen-free mice exposed to neonatal infection with mouse enterovirus or to malnutrition during early life. Metabolic activity was determined by measuring the turnover of cyclic AMP-8-14C to respiratory 14CO2, its incorporation into various organs and plasma, and the binding activity of synaptosome for cyclic AMP.Keywords
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